Services :: Surveillance

Increasing antimicrobial resistance in a number of pathogens is becoming a serious issue and obviously has an impact on treatment. We identify the molecular mechanisms of resistance, examine resistance selection in vitro and in vivo, and carry out antimicrobial susceptibility testing according to NCCLS guidelines.

Some of our services which are of use in surveillance studies and epidemiological investigations are serotyping, PFGE, and MIC determination.

Related Research Articles

• Athamna A, Athamna M, Abu-Rashed N, Medlej B, Bast DJ, Rubinstein E. Selection of Bacillus anthracis isolates resistant to antibiotics. J Antimicrob Chemother. 54(2):424-428. (2004)
• Davidson, R., Calvalcanti, R., Brunton, J.L., Bast, D.J., de Azavedo, J.C.S.,Kibsey, P., Fleming, C., Low, D.E. Resistance to levofloxacin and failure of treatment of pneumococcal pneumonia. N Engl J Med. 346:747-750. (2002)
• Weiss K. Restieri C. Gauthier R. Laverdiere M. McGeer A. Davidson RJ. Kilburn L. Bast DJ. de Azavedo J. Low DE. A nosocomial outbreak of fluoroquinolone-resistant Streptococcus pneumoniae. Clin Infect Dis. 33(4):517-522. (2001)
• de Azavedo, JCS., Yeung, RH., Bast, DJ., Duncan, CL., Borgia, SB., and Low, DE. Prevalence and mechanisms of macrolide resistance in clinical isolates of Group A Streptococci from Ontario, Canada. Antimicrob Agents Chemother. 43:2144-2147. (1999)