Education Materials

Mount Sinai Hospital is a University of Toronto patient care, teaching, and research centre.
Mount Sinai Hospital is a University of Toronto patient care, teaching, and research centre.

Staff Directory
Donald E. Low, M.D., FRCPC
Department of Microbiology,
Mount Sinai Hospital, Room 1485
600 University Ave, Toronto Ontario, M5G 1X5
Phone: (416) 586-4435
Fax: (416) 586-8746



Dr. Low, a fellow of the Royal College of Physicians and Surgeons of Canada, completed his undergraduate training and postgraduate training in medicine and infectious diseases at the University of Manitoba and his training in Medical Microbiology at the University of Toronto. He is a Fellow of the American Academy of Microbiology.

Dr. Low's primary research interests are in the study of the epidemiology and the mechanisms of antimicrobial resistance in community and hospital pathogens. Other research interests include the epidemiology, pathogenesis, and treatment of streptococcal diseases. His group is recognized internationally for their Canadian population-based surveillance programs for the study of antimicrobial resistance and infectious diseases.

A recognized authority in microbiology and infectious diseases, Dr. Low has published more than 170 papers in peer-reviewed journals and is a reviewer for several organizations including the Medical Research Council, Health and Welfare Canada, New England Journal of Medicine, Journal of American Medical Association, and the Proceedings of the National Academy of Science. He is also an Associate Editor of the Canadian Journal of Infectious Diseases.

Dr. Low is Head of the Department of Microbiology at the University Health Network and Mount Sinai Hospital, a diagnostic laboratory serving 10 hospitals in the Greater Toronto Area. He is a Professor at the University of Toronto in the Department of Laboratory Medicine and Pathobiology and Department of Medicine. He is currently Head of the Division of Microbiology in the Department of Laboratory Medicine and Pathobiology.

Recent Publications

  1. Wolter N, Smith AM, Low DE, Klugman KP.
    High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae.
    Antimicrob Agents Chemother. 51(3):1092-5, 3/8/2007.

  2. Mehta S, McGeer A, Low DE, Hallett D, Bowman DJ, Grossman SL, Stewart TE.
    Morbidity and mortality of patients with invasive group A streptococcal infections admitted to the ICU.
    Chest 130(6):1679-86., 12/1/2006.

  3. Hanselman BA, Kruth SA, Rousseau J, Low DE, Willey BM, McGeer A, Weese JS.
    Methicillin-resistant Staphylococcus aureus colonization in veterinary personnel.
    Emerg Infect Dis. 12(12):1933-8, 12/1/2006.

  4. Bast DJ, Dresser L, Duncan CL, Walker SE, Mandell LA, Low DE, de Azavedo JC.
    Short-course therapy of gemifloxacin effective against pneumococcal pneumonia in mice
    J Chemother 18(6):634-40, 12/1/2006.

  5. Lowe DO, Mamdani MM, Kopp A, Low DE, Juurlink DN.
    Proton pump inhibitors and hospitalization for Clostridium difficile-associated disease: a population-based study.
    Clin Infect Dis. 43(10):1272-6., 11/15/2006.

  6. Valiquette L, Low DE, Chow R, McGeer AJ.
    A survey of physician's attitudes regarding management of severe group A streptococcal infections.
    Scand J Infect Diseases. 38(11-12):977-82., 11/1/2006.

  7. Roberts A, Bitnun A, McGeer A, Tran D, Yau Y, Simpson K, Green K, Lowe DE, Ford-Jones EL.
    Laboratory-confirmed influenza-associated hospitalizations among children in the metropolitan Toronto and Peel region by active surveillance, 2004-2005.
    Can Commun Dis Rep. 32(18):203-7., 9/15/2006.

  8. Daneman N, McGeer A, Green K, Low DE; Toronto Invasive Bacterial Diseases Network. Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
    Macrolide resistance in bacteremic pneumococcal disease: implications for patient management.
    Clin Infect Dis. 43(4):432-8., 8/15/2006.

  9. De Azavedo JC, Duncan CL, Kilburn L, Downar J, Kong B, Lad S, Low DE, Bast DJ.
    Relative potential for selection of quinolone-resistance-determining-region mutations in Streptococcus pneumoniae by gemifloxacin, gatifloxacin and moxifloxacin.
    J Chemother 18(4):373-8., 8/1/2006.

  10. Olsen CW, Karasin AI, Carman S, Li Y, Bastien N, Ojkic D, Alves D, Charbonneau G, Henning BM, Low DE, Burton L, Broukhanski G.
    Triple reassortant H3N2 influenza A viruses, Canada, 2005.
    Emerg Infect Dis. 12(7):1132-5, 7/1/2006.

For More Articles by Dr. Low Click Here

Advisory Committee/External Organizations

  • Chairman, Microbiology Committee, Quality Management Program, Laboratory Services, Ontario Medical Association
  • Member, National Committee on Clinical Laboratory Standards Subcommittee on Antimicrobial Susceptibility Testing, Wayne, PA, USA
  • Editorial board, Journal of Antimicrobial Chemotherapy
  • Editorial Board, Antimicrobial Agents and Chemotherapy


  • 1999. Janssen-Ortho Distinguished Service Award, Canadian Infectious Disease Society
  • 1999. Louis Weinstein Award for the best clinical article published in Clinical Infectious Diseases between July 1998 and June 1999.
  • 2000. Divisional A. Lecture, Lost opportunities, future challenges. Surveillance and Its Role in R&D Symposium. 100th American Society for Microbiology General Meeting, Los Angeles, CA, 2000.
  • 2001. 2001 BD Award for Research in Clinical Microbiology, American Academy of Microbiology.
  • 2001. Divisional C. Lecture, Examining Resistance in Streptococcus pneumoniae: Perspectives. 101st American Society for Microbiology General Meeting, Orlando, Florida, 2001.
This website has been made possible through an unrestricted educational grant from Pfizer Canada Inc.
Copyright 1999-2007 Department of Microbiology, Mount Sinai Hospital, Toronto, Canada. All rights reserved.