An Ecologic Study of Antimicrobial Resistance in Long Term Care Facilities in Canada and the United States

Antibiotic use in long-term care facilities has been implicated as a risk factor for the isolation of multi-drug resistant bacteria such as MRSA, VRE and multi -drug resistant coliforms. Rates of colonization and infection with these organisms appear to be higher in the United States than in Canada. The reason for this difference is unclear. This study will take advantage of the variation between the two countries to try and understand the relationship between antibiotic use and bacterial resistance. An ecologic survey will be carried out in nursing homes in Canada and the United States to determine rate of multi-drug resistant bacteria compared to rates of antibiotic utilization in these same facilities.

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