|
Ian E. Crandall, MSc, D.Phil
Research Scientist
University of Toronto
MaRS Centre, Room 10-356
10th Floor
Toronto Medical Discovery Tower, 101 College St
Toronto, Ontario, M5G 1L7
Phone: (416) 978-0356
Fax: (416) 978-8765
E-mail: ian.crandall@utoronto.ca |
Biography
Dr. Ian Crandall received a Bachelor of Science and
a Master of Science in biochemistry from Queen's University before
heading to Oxford to obtain his Doctor of Philosophy (D.Phil)
in developmental biology from Oxford university in 1987. He spent
a Post Doctoral Fellowship at the University of California working
on Plasmodium falciparum (human malaria) before coming
to Toronto to continue his work.
Dr. Crandall is interested in Tropical Diseases and
world health with a primary research interest in the mechanisms
whereby malaria is able to sequester and avoid its human host's
immune system. He is also actively testing and developing new
anti-malarial compounds.
Dr. Crandall is presently a Staff Scientist at the
Toronto Medical Laboratories and oversees the operation of the
Parasitology section and is responsible for teaching laboratory
techniques to the local hospital residents. He is also an assistant
Professor in the departments of Laboratory Medicine and Pathobiology
and the Department of Medicine at the University of Toronto and
is currently responsible for teaching microbiology to Pharmacy
students.
Recent Publications
- Bello AM, Poduch E, Fujihashi M, Amani M, Li Y, Crandall I, Hui R, Lee PI, Kain KC, Pai EF, Kotra LP
A potent, covalent inhibitor of orotidine 5-monophosphate decarboxylase with antimalarial activity
J Med Microbiol. 50(5):915-21, 3/8/2007.
- Ciach M, Zong K, Kain KC, Crandall I.
Reversal of mefloquine and quinine resistance in Plasmodium falciparum with NP30.
Antimicrob Agents Chemother. 47(8):2393-2396, 8/1/2003.
- Labbe AC. Patel S. Crandall I. Kain KC.
A molecular surveillance system for global patterns of drug resistance in imported malaria
Emerg Infect Dis. 9(1):33-36, 1/1/2003.
- Richardson DC. Ciach M. Zhong KJ. Crandall I. Kain KC.
Evaluation of the Makromed Dipstick Assay versus PCR for Diagnosis of Plasmodium falciparum Malaria in Returned Travelers.
J Clin Microbiol. 40(12):4528-4530, 12/1/2002.
- Kisilevsky R. Crandall I. Szarek WA. Bhat S. Tan C. Boudreau L. Kain KC.
Short-chain aliphatic polysulfonates inhibit the entry of Plasmodium into red blood cells.
Antimicrob Agents Chemother. 46(8):2619-2626, 8/1/2002.
- Porro GA, Lee JH, de Azavedo J, Crandall I, Whitehead T, Tullis E, Ganz T, Liu M, Slutsky AS, Zhang H.
Direct and indirect bacterial killing functions of neutrophil defensins in lung explants.
Amer J Physio. 281(5):L1240-1247, 11/1/2001.
- Guy RA. Maguire GF. Crandall I. Connelly PW. Kain KC.
Characterization of peroxynitrite-oxidized low density lipoprotein binding to human CD36.
Atherosclerosis. 155(1):19-28, 3/1/2001.
- Yau YC. Crandall I. Kain KC.
Development of monoclonal antibodies which specifically recognize Entamoeba histolytica in preserved stool samples.
J Clin Microbiol. 39(2):716-719, 2/1/2001.
- Crandall I, Charuk J, Kain KC
Nonylphenolethoxylates as malarial chloroquine resistance reversal agents
Antimicrob Agents Chemother. 44(9):2431-4, 9/1/2000.
- Crandall I, Guy RA, Maguire GF, Connelly PW, Kain KC
Plasmodium falciparum-infected erythrocytes and oxidized low-density lipoprotein bind to separate domains of CD36
J Infect Dis. 180(2):473-9, 8/1/1999.
This website has been made possible through an unrestricted educational grant from
Pfizer Canada Inc. |
|
